Copy Number Variation
In order to explore the heterogeneity of cell genotype, phenotype, and function within a complex cell population, single-cell sequencing technologies like 10X Genomics, BD Phrapsody, and Illumina Hiseq have evolved. These technologies enable us to characterize the genome, transcriptome, and epigenomics of individual cells. Single cell copy number variation (CNV) is a significant form of…